This book is an insightful guide to the dynamic biochemical processes that govern blood’s function and disorders. It explores the molecular structure of blood components – red and white blood cells, platelets, plasma proteins, and clotting factors, and how they interact to maintain balance and respond to challenges. Designed for students, educators, researchers, and healthcare professionals, it explains key biochemical mechanisms behind oxygen transport, immune defence, haemostasis, and inflammation. The book also examines pathological changes in anaemia, haemophilia, leukaemia, sepsis, and clotting disorders, highlighting molecular triggers and pathways. A unique strength is its translational focus, connecting fundamental biochemistry to clinical practice, diagnostics, and therapies. Chapters on blood-based biomarkers, targeted treatments, and the biochemical impact of diseases like COVID-19 offer a modern perspective on haematology research. Written in an engaging style, this book helps readers appreciate blood’s complexity and its vital role in precision medicine and personalised healthcare.
The use of glycated haemoglobin was a major step in antidiabetic treatment and led to the identification of cell receptors. The aim of this study is to explore how one such cell receptor, RAGE, offers new therapeutic possibilities for diabetes, ageing, and Alzheimer’s disease.
